One day, Horton the elephant hears a cry for help coming from a speck of dust. Even though he can't see anyone on the speck, he decides to help it. Good thing since as it turns out, the speck of dust is home to the Whos, who live in their city of Whoville. Horton agrees to help protect the Whos and their home. Unfortunately for Horton, this gives him nothing but torment from his neighbors. They refuse to believe that anything could survive on the...

When Joel discovers that his girlfriend, Clementine, has had their tumultuous relationship erased from her mind through an experimental scientific procedure, he decides to ease his own pain by getting the same treatment. But, as each memory of Clementine is systematically eliminated, Joel suddenly realizes how much he still loves her and desperately attempts to reverse the process.