FBI agent Gabriel Dean rushes into action to protect his pregnant wife, homicide detective Jane Rizzoli, when she is taken hostage along with others at the hospital by Nicholas Tennant, a black-ops agent in possession of high-level government secrets.

Something unspeakably chilling is heating up The City of Angels. Beneath the famed La Brea Tar Pits, a raging volcano has formed, raining a storm of deadly fire bombs and an endless tide of white-hot lava upon the stunned city.