Gulliver leads a life of luxury with his master. But when his master falls in love with a woman who is allergic to dogs, Gulliver is sent to a new home. He finds himself with a family of raucous human beings and three mutts. But just as Gulliver begins to make a grudging peace with his new reality, he gets swept up in a harrowing new adventure.

Montague, an artistic young rat living beneath the streets of New York City, thinks he can do nothing to save his friends from extermination until he achieves a better understanding of both himself and his ne'er-do-well uncle.

Musical Maggie Mad-Rat leaves her home in Africa to attend her cousin Montague's wedding in New York City, where she meets family and makes new friends, including the unique Randal Reese-Rat.