Shaun Murphy, a young surgeon with autism and savant syndrome, relocates from a quiet country life to join a prestigious hospital surgical unit. Alone in the world and unable to personally connect with those around him, Shaun uses his extraordinary medical gifts to save lives and challenge the skepticism of his colleagues.

Detective Mac Taylor and his forensics team face the shocking loss of one of its members, followed by a provocative new addition to the force, Lindsay Monroe.

The show is about a young surgeon with autism who is recruited to work at a pediatric unit of a hospital. The hospital is known for treating many of the toughest cases a surgeon could ever see, but with autism comes clarity that most surgeons will never have. The television series focuses on the relationship between the doctor and patient, and how a man who cannot relate to the people who he tries to help.